01. Digestive tract (Esophagus, Stomach, Duodenum, Small intestine, Large intestine, Anus)
02. Liver
03. Pancreas
04. Gallbladder & Bile ducts
These are the main components.
Major Diseases
This Gastrointestinal (Digestive Tract) Care Program covers not only the diseases outlined in the red box on the chart but also Functional Dyspepsia (FD), which presents chronic epigastric pain, bloating, and discomfort without any apparent abnormality causing the symptoms.
What is Functional Dyspepsia (FD)?
Definition of Functional Dyspepsia
A condition where chronic epigastric pain, bloating, and other abdominal symptoms centered around the upper stomach occur despite the absence of organic, systemic, or metabolic disease as the cause.
Dyspepsia originates from a Greek word meaning “indigestion.”
Until now, such symptoms were often diagnosed as “chronic gastritis.” However, chronic gastritis refers to “inflammation in the stomach” (most often caused by Helicobacter pylori), but it has become clear that inflammation and symptoms are not necessarily related.
Therefore, around 1990, the American Gastroenterological Association introduced the concept of Functional Dyspepsia (FD).
Currently, reports suggest that the prevalence of functional dyspepsia is around 15%, making it a common condition. While it does not affect life expectancy, it impacts the quality of life (QOL) and requires appropriate treatment.
Causes
There may be a single cause, or multiple factors may combine to trigger symptoms.
When gastric and duodenal motility is impaired: This includes gastric emptying disorders and abnormal adaptive relaxation. Both delayed and excessively rapid gastric emptying can be related to symptoms, while impaired gastric adaptive relaxation is linked to early satiety.
Gastric Emptying: The process of moving food from the stomach to the duodenum. Gastric Adaptive Relaxation: The stomach’s ability to expand and store food during meals.
When gastric and duodenal hypersensitivity occurs: Symptoms appear with less gastric distension compared to healthy individuals. Additionally, hypersensitivity to gastric acid and fat in the duodenum can trigger symptoms.
Psychological factors (especially anxiety or history of abuse): The brain and gut are closely related. Anxiety, depression, or childhood abuse history may alter gastrointestinal motility and sensation.
When gastric acid is the cause: Gastric acid can irritate the mucosa of the stomach and duodenum, affecting motility and sensitivity.
When Helicobacter pylori infection is the cause: Symptoms may improve after H. pylori eradication.
Genetic factors
History of infectious gastroenteritis such as Salmonella infection
Unhealthy lifestyle habits such as alcohol consumption, smoking, and poor sleep
Gastric morphology: Conditions like “hourglass stomach,” where the upper part of the stomach is expanded and deformed, may be related to symptoms.
Examinations & Diagnosis
To rule out diseases such as gastric cancer, gastric ulcers, or duodenal ulcers, an endoscopy of the stomach, a Helicobacter pylori test, and if necessary, blood tests, ultrasound, and abdominal CT scans are conducted.
Diagnostic Criteria
・Presence of chronic stomach pain or bloating symptoms. ※ Medically, this includes postprandial fullness, early satiety, epigastric pain, and epigastric burning sensation.
・No presence of diseases such as gastric cancer or gastric ulcers detected by endoscopy.
General Treatment
There are primarily two causes considered for the symptoms of FD.
・When abnormalities in the stomach’s function are perceived as symptoms
The main triggers for abnormalities are gastric movement and gastric acid. If the process of moving food from the stomach to the duodenum does not work well, symptoms such as bloating and pain may occur. For improvement, gastrointestinal motility improving drugs are used. Additionally, when gastric acid secretion causes pain or when excess gastric acid flows into the duodenum, causing nausea, acid secretion inhibitors are used to suppress the gastric acid secretion.
・When normal stomach function is excessively sensitive, causing symptoms
This occurs when there is hypersensitivity to various stimuli. It is difficult to suppress an overly sensitive brain state, but some anti-anxiety drugs and antidepressants have been shown to improve FD symptoms. Furthermore, herbal medicine has been shown to improve FD symptoms by improving stomach movement or increasing appetite, although there is not enough evidence to fully support this.
Treatment is done by consulting with the patient and the doctor to test which medications work best, and sometimes using a combination of medications with different effects. Under the guidance of a reliable doctor, proper medication, along with lifestyle and dietary improvements, is essential.
Cure Rate and Associated Diseases
Unfortunately, it is not yet clear how to prevent recurrence or which individuals are more likely to relapse, but after treatment when symptoms disappear, it is said that about 20% relapse within a few months.
The causes are thought to involve psychosocial factors, and many individuals with anxiety, depression, and neurotic disorders are also affected. Between 25% and 50% of people are said to have conditions such as gastroesophageal reflux disease, irritable bowel syndrome, or chronic constipation. In some cases, diseases of the gallbladder or pancreas may be hidden.
Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome (IBS)
It is a disease suspected when abdominal pain and discomfort are accompanied by bowel irregularities, such as constipation or diarrhea (in terms of frequency and shape), that last for several months or more. It is assumed that there are no organic diseases like tumors or inflammation in the large intestine.
About 10% of Japanese people are said to have this disease, making it one of the common diseases. It is more common in women and decreases with age. While not life-threatening, the symptoms of abdominal pain, constipation, diarrhea, and anxiety can significantly impact daily life.
Causes
The intestines not only aid in digestion and absorption but also expel waste as stool. Therefore, intestinal contraction movements are necessary to move food toward the anus and sensory functions to detect changes in the intestines. This function is controlled through the exchange of information between the brain and the intestines. When stressed, anxiety may cause excessive contraction movements and hypersensitivity in the intestines. This strong hypersensitivity is a characteristic feature of IBS. Stress amplifies signals from the brain to the intestines, altering gastrointestinal motility through autonomic nerves and endocrine systems.
The cause of IBS is unknown. However, it is known that after an infectious gastroenteritis caused by bacteria or viruses, people are more likely to develop IBS upon recovery.
Examination and Diagnosis
Since Irritable Bowel Syndrome (IBS) shows characteristic abdominal symptoms and changes in bowel movements, it is sometimes diagnosed based on just a medical interview without special tests.
However, to confirm that there are no serious conditions like colon cancer or inflammatory bowel disease, or if the symptoms are severe or do not improve with treatment, tests such as blood tests, abdominal ultrasound, abdominal CT scans, fecal occult blood tests, colonoscopy, and colon contrast radiography may be conducted.
Diagnostic Criteria (Rome III Criteria)
During the past 3 months, abdominal pain or discomfort occurring on at least 3 days per month and showing at least two of the following characteristics:
1) Symptoms are relieved by bowel movements
2) The frequency of bowel movements changes with the symptoms (increased or decreased)
3) The form (appearance) of the stool changes with the symptoms (becoming softer or harder)
Type Classification
The Bristol Stool Form Scale is used to classify the stool form and frequency into the following 4 types:
General Treatment Methods
・First, lifestyle improvements are recommended.
Avoid overeating, large meals, and pay attention to a balanced diet, eat regularly, avoid stress, and ensure sufficient sleep and rest. Limit stimulants, high-fat foods, and alcohol.
・If symptoms do not improve after lifestyle changes, medication therapy may be considered.
> Initially, gastrointestinal motility regulators or probiotics (such as bifidobacteria or lactobacillus, beneficial bacteria for the body), and medications to adjust stool water balance may be used. These drugs are used for both diarrhea and constipation symptoms.
> For those with diarrhea type, serotonin 3 receptor antagonists (5-HT3 antagonists) are used to improve abnormal intestinal motility.
> For those with constipation type, mucosal epithelial function-modifying drugs are used to soften stools.
For diarrhea, anti-diarrheal drugs may be used, and anticholinergic drugs for abdominal pain; laxatives may be used as supplementary or as needed for constipation.
・Non-pharmacological treatments include dietary therapy and exercise therapy.
Carbohydrates, high-fat foods, coffee, alcohol, and spices may trigger abdominal pain and changes in bowel movements. If certain foods trigger symptoms, they should be avoided. Fermented foods like yogurt may be effective in reducing symptoms. Additionally, fiber-rich foods are effective for constipation types.
Moderate exercise is also expected to help alleviate symptoms. Aim for sustainable levels of physical activity.
・If IBS symptoms do not improve with pharmacotherapy, psychotherapy may be effective in some cases.
When stress or psychological factors are considered to play a significant role, treatment may involve a combination of psychotherapy and pharmacotherapy.
Abdominal pain and bowel irregularities tend to improve with age, and the likelihood of developing a disease is lower. However, the type of bowel irregularity may change. Compared to healthy individuals, those who experience stomach pain, bloating (functional dyspepsia), heartburn, and acid reflux (gastroesophageal reflux disease) are more than twice as likely to have these symptoms. Additionally, depression and anxiety are more likely to co-occur, and the impact on daily life may be more significant.
Moreover, it has been reported that IBS may lead to a higher risk of developing ulcerative colitis or Crohn’s disease. If you notice blood in your stool or unexplained weight loss, it is advisable to seek medical attention.
Prevention
Currently, there are no studies proving IBS can be prevented, but some risk factors for IBS are known. Among these, the risk factors that can be reduced by individuals include stress, depressive tendencies, excessive concern about physical abnormalities, and smoking.
Getting adequate sleep, maintaining a regular lifestyle, and practicing relaxation methods suited to you—without relying on alcohol or tobacco—are helpful. Additionally, making dietary adjustments, exercising, and consuming probiotics may help prevent IBS.
Interventions Available Only at Medical Japan
Autonomic Nervous System and Peripheral Blood Flow Diagnosis
While providing dietary and lifestyle modification advice to improve symptoms, we also check the status of the autonomic nervous system, which is influenced by stress, and the blood flow to internal organs. Depending on the degree and duration of stress, it is possible to identify whether the problem lies in the sympathetic or parasympathetic nervous system, and what type of care is required.
Improving Internal Organ Blood Flow: Intervention Example Using Moxibustion
Moxibustion has been confirmed to improve the blood flow to internal organs and activate the digestive system and metabolism. For the elderly, the decline in basal metabolism and indigestion can be major obstacles to dieting, but these issues can be improved through moxibustion.
This patient had been suffering from chronic indigestion and constipation. By regularly performing moxibustion, blood flow to the internal organs improved, the digestive system became more active, and bowel movements became smoother. Furthermore, with improved metabolism, the patient experienced weight loss. This is an example of successfully managing weight healthily with a diet plan incorporating moxibustion.
Gastrointestinal Care Breathing Exercises
We teach exercises and breathing techniques that can be practiced daily. Through proper instruction by medical professionals with national qualifications, we strive to improve symptoms and prevent recurrence.